Friday, 20 July 2012

International Apex Tramadol HCl




International Apex Tramadol HCl may be available in the countries listed below.


Ingredient matches for International Apex Tramadol HCl



Tramadol

Tramadol hydrochloride (a derivative of Tramadol) is reported as an ingredient of International Apex Tramadol HCl in the following countries:


  • Philippines

International Drug Name Search

Monday, 16 July 2012

Ictammolo Alvita




Ictammolo Alvita may be available in the countries listed below.


Ingredient matches for Ictammolo Alvita



Ichthammol

Ichthammol is reported as an ingredient of Ictammolo Alvita in the following countries:


  • Italy

International Drug Name Search

Saturday, 14 July 2012

Ultiva


Pronunciation: rem-i-FEN-ta-nil
Generic Name: Remifentanil
Brand Name: Ultiva


Ultiva is used for:

Preventing and treating pain during and after procedures and surgery.


Ultiva is a narcotic pain reliever. It works by dulling the pain perception center in the brain.


Do NOT use Ultiva if:


  • you are allergic to any ingredient in Ultiva or to similar medicines (eg, fentanyl)

  • you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.



Before using Ultiva:


Some medical conditions may interact with Ultiva. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have heart or breathing problems

  • if you have a history of substance abuse or dependence problems

Some MEDICINES MAY INTERACT with Ultiva. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Alcohol, amiodarone, benzodiazepines (eg, alprazolam), cimetidine, or sodium oxybate (GHB) because the side effects of Ultiva may be increased

  • Naltrexone because the effectiveness of Ultiva may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ultiva may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Ultiva:


Use Ultiva as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Ultiva is usually administered as an injection at your doctor's office, hospital, or clinic. Ask your doctor or pharmacist any questions you may have about Ultiva.

  • If you miss a dose of Ultiva, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Ultiva.



Important safety information:


  • Ultiva may cause dizziness or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Ultiva. Using Ultiva alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

  • Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Ultiva. Ultiva will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.

  • Use Ultiva with caution in the ELDERLY because they may be more sensitive to its effects.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Ultiva during pregnancy. It is unknown if Ultiva is excreted in breast milk. If you are or will be breast-feeding while you are using Ultiva, check with your doctor or pharmacist to discuss the risks to your baby.

When used for long periods of time or at high doses, Ultiva may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Ultiva stops working well. Do not take more then prescribed.


When used for long periods of time or at high doses, some people develop a need to continue taking Ultiva. This is known as DEPENDENCE or addiction.


If you suddenly stop taking Ultiva, you may experience WITHDRAWAL symptoms, including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping.



Possible side effects of Ultiva:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Changes in vision; chills; dizziness; drowsiness; fever; headache; itching; nausea; shivering; sweating; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fast or slow heartbeat; interrupted breathing; lightheadedness; muscle tightness; pain, redness, or swelling at the injection site; seizures.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Ultiva side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include difficulty breathing; dizziness; lightheadedness; seizures; slow heartbeat; tightening of muscles in the chest.


Proper storage of Ultiva:

Ultiva is usually handled and stored by a health care provider. If you are using Ultiva at home, store Ultiva as directed by your pharmacist or health care provider. Keep Ultiva, as well as needles and syringes, out of the reach of children and away from pets.


General information:


  • If you have any questions about Ultiva, please talk with your doctor, pharmacist, or other health care provider.

  • Ultiva is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Ultiva. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Ultiva resources


  • Ultiva Side Effects (in more detail)
  • Ultiva Use in Pregnancy & Breastfeeding
  • Ultiva Drug Interactions
  • Ultiva Support Group
  • 0 Reviews for Ultiva - Add your own review/rating


  • Ultiva Prescribing Information (FDA)

  • Ultiva Concise Consumer Information (Cerner Multum)

  • Ultiva Monograph (AHFS DI)

  • Ultiva Advanced Consumer (Micromedex) - Includes Dosage Information



Compare Ultiva with other medications


  • Anesthesia

Friday, 13 July 2012

Boots Pharmacy Anaesthetic Throat Spray





Boots Pharmacy Anaesthetic Throat Spray



(Lidocaine Hydrochloride)




Specifically to:



Relieve severe sore throat pain



20 ml e



Read all of this carton for full instructions.




A local anaesthetic spray to provide direct and soothing relief from the pain of severe sore throats.





Before you use this medicine




Do not use:



  • If you are allergic to any of the ingredients

  • If you have asthma, or difficulty breathing

  • If you are under 12 years of age




Talk to your pharmacist or doctor:



  • If you are receiving any medical treatment

  • If you have a high fever, headache, feel sick or are being sick as well as having a sore throat

  • If you are pregnant or breastfeeding



This spray may cause your tongue to become numb. You must take care when eating or drinking hot foods or drinks.





How to use this medicine



Use at the back of the throat only.



Do not breathe in when you use the spray, or get the spray in your eyes.



To spray: Swing the nozzle through 90° and press.



Before first use or after storing the spray for a long time: Press the spray 3 times away from the face into a sink.





Adults and children of 12 years and over

Three sprays at the back of the throat every 3 hours, if you need to.

Don’t use more than 6 times in any 24 hours.




Do not use for children under 12 years.



Do not use more than the amount recommended above.




If you use too much:



Talk to a doctor straight away. Take your medicine with you.



If symptoms do not go away, talk to your doctor.






Possible side effects



Most people will not have problems, but some may get some.



If you get any of these serious side effects, stop using the spray.



See a doctor at once:



  • Difficulty in breathing, swelling of the face, neck, tongue or throat (severe allergic reactions)

If you notice any side effect not listed here, please tell your pharmacist or doctor.



Keep all medicines out of the sight and reach of children.



Use by the date on the side of the carton.





Active ingredient



This liquid contains Lidocaine Hydrochloride 2% w/v.



Also contains: purified water, ethanol (30 vol %), sorbitol (E420), sodium citrate, saccharin, quinoline yellow (E104), patent blue V (E131), flavours (peppermint, levomenthol, aniseed).




PL00014/0430



P



Text prepared 10/07




Manufactured for the Marketing Authorisation holder




Boots Pharmacy

Nottingham

NG2 3AA



by




The Boots Company PLC

Nottingham

NG2 3AA




Contains approximately 150 sprays.



If you need more advice ask your pharmacist.



BTC22021 vE 15/05/08






Thursday, 12 July 2012

NeuTrexin


Generic Name: trimetrexate (Intravenous route)

trye-me-TREX-ate

Intravenous routePowder for Solution

Trimetrexate glucuronate for injection must be used with concurrent leucovorin (leucovorin protection) to avoid potentially serious or life-threatening toxicities .


Trimetrexate glucuronate for injection must be used with concurrent leucovorin (leucovorin protection) to avoid potentially serious or life-threatening toxicities .



Commonly used brand name(s):


In the U.S.


  • NeuTrexin

Available Dosage Forms:


  • Powder for Solution

Therapeutic Class: Antibiotic


Pharmacologic Class: Antimetabolite


Uses For NeuTrexin

Trimetrexate is used, together with leucovorin, to treat Pneumocystis carinii pneumonia (PCP), a very serious kind of pneumonia. This kind of pneumonia occurs commonly in patients whose immune system is not working normally, such as cancer patients, transplant patients, and patients with acquired immune deficiency syndrome (AIDS).


Trimetrexate may cause some serious, even life-threatening, side effects. To prevent these effects, you must take another medicine, leucovorin, together with trimetrexate and for 3 days after you stop receiving trimetrexate. Before you begin treatment with trimetrexate, you and your doctor should talk about the good this medicine will do as well as the risks of using it.


Trimetrexate is to be administered only by or under the immediate supervision of your doctor.


Products containing trimetrexate were withdrawn from the market by MedImmune in March 2007 .


Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, trimetrexate is used in certain patients with the following medical condition:


  • Cancer of the colon

Before Using NeuTrexin


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


This medicine has been tested in a limited number of children younger than 18 years of age. Trimetrexate can cause serious side effects in any patient. However, in effective doses, this medicine did not cause different side effects or problems in the few children who received it than it does in adults.


Geriatric


Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of trimetrexate in the elderly with use in other age groups.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersDStudies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.


  • Rotavirus Vaccine, Live

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Bacillus of Calmette and Guerin Vaccine, Live

  • Influenza Virus Vaccine, Live

  • Measles Virus Vaccine, Live

  • Mumps Virus Vaccine, Live

  • Poliovirus Vaccine, Live

  • Rotavirus Vaccine, Live

  • Rubella Virus Vaccine, Live

  • Smallpox Vaccine

  • Typhoid Vaccine

  • Varicella Virus Vaccine

  • Yellow Fever Vaccine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Cimetidine

  • Clotrimazole

  • Erythromycin

  • Fluconazole

  • Itraconazole

  • Ketoconazole

  • Miconazole

  • Rifabutin

  • Rifampin

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Anemia or

  • Blood problems or

  • Low platelet count or

  • Low white blood cell count—Trimetrexate may make any blood diseases that you have worse.

  • Mouth ulcers or other mouth sores or

  • Stomach ulcer or other stomach or intestinal problems—Trimetrexate may make these conditions worse.

  • Kidney disease or

  • Liver disease—Kidney or liver disease may increase the chance of side effects from trimetrexate.

Proper Use of NeuTrexin


When you take leucovorin:


  • Leucovorin must be taken with trimetrexate to help prevent very serious, possibly life-threatening, unwanted side effects. Leucovorin should be taken during trimetrexate treatment and for 3 days after trimetrexate is stopped. It is very important to take this medicine exactly as your doctor told you. Failure to do this can result in very serious side effects.

  • Take oral leucovorin exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not stop taking this medicine without checking with your doctor first.

  • Oral leucovorin works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. If you need help in planning the best times to take your medicine, check with your health care professional.

  • If you vomit shortly after taking an oral dose of leucovorin, check with your doctor. You will be told whether to take the dose again or to wait until the next scheduled dose.

Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For trimetrexate

  • For the treatment of Pneumocystis carinii pneumonia:
    • For injection dosage form:
      • Adults— 45 milligrams per square meter of body surface area (mg/m2) injected into a vein once a day for twenty-one days. Your doctor will check your blood counts and may change your dose based on these counts. Your doctor may want to give you a dose you based on how much you weigh. Your dose will be determined by your doctor.

      • Children and teenagers—Use and dose must be determined by your doctor.



  • For leucovorin

  • For the prevention of serious side effects of trimetrexate in the treatment of Pneumocystis carinii pneumonia:
    • For the oral or injection dosage forms:
      • Adults—20 milligrams per square meter of body surface area (mg/m 2) taken by mouth or injected into a vein every six hours for twenty-four days. Your doctor will check your blood counts and may change your dose based on these counts. Your doctor may want to give you a dose you based on how much you weigh. Your dose will be determined by your doctor.

      • Children and teenagers—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Precautions While Using NeuTrexin


If your symptoms do not improve within a few days, or if they become worse, check with your doctor.


It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.


Trimetrexate can lower the number of white blood cells in your blood temporarily, increasing your chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:


  • If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.

  • Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry stools; blood in urine or stools; or pinpoint red spots on your skin.

  • Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done.

  • Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters.

Check with your doctor right away if you experience symptoms of an allergic reaction such as cough, difficulty swallowing, dizziness, fainting or loss of consciousness, fast heartbeat, fast or irregular breathing, hives, itching, puffiness or swelling of the eyelids or around the eyes, face, lips or tongue, shortness of breath, skin rash, swelling of eyes or eyelids, tightness in chest, trouble in breathing, unusual tiredness or weakness, and/or wheezing .


NeuTrexin Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


More common
  • Abdominal pain or tenderness

  • black, tarry stools

  • blood in urine or stools

  • clay-colored stools

  • dark urine

  • decreased appetite

  • fever and sore throat

  • headache

  • itching

  • loss of appetite

  • nausea and vomiting

  • pinpoint red spots on skin

  • skin rash

  • swelling of feet or lower legs

  • unusual bleeding or bruising

  • unusual tiredness or weakness

  • yellow eyes or skin

Less common
  • Abdominal cramps

  • coma

  • confusion

  • convulsions

  • decreased urine output

  • difficulty in breathing

  • dizziness

  • fast or irregular heartbeat

  • hypocalcemia

  • increased thirst

  • mood or mental changes

  • muscle cramps in hands, arms, feet, legs, or face

  • muscle pain

  • mouth sores or ulcers

  • numbness and tingling around the mouth, fingertips, or feet

  • skin rash and itching

  • shortness of breath

  • tremor

Rare
  • Cough

  • difficulty swallowing

  • fainting or loss of consciousness

  • fast or irregular breathing

  • hives

  • puffiness or swelling of the eyelids or around the eyes, face, lips or tongue

  • swelling of eyes or eyelids

  • tightness in chest

  • trouble in breathing

  • wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Less common
  • Fatigue

  • stomach pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: NeuTrexin side effects (in more detail)



The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.


More NeuTrexin resources


  • NeuTrexin Side Effects (in more detail)
  • NeuTrexin Use in Pregnancy & Breastfeeding
  • NeuTrexin Drug Interactions
  • NeuTrexin Support Group
  • 0 Reviews for NeuTrexin - Add your own review/rating


  • Neutrexin Prescribing Information (FDA)

  • Neutrexin MedFacts Consumer Leaflet (Wolters Kluwer)



Compare NeuTrexin with other medications


  • Pneumocystis Pneumonia

Monday, 9 July 2012

Lopressor



Pronunciation: MET-oh-PROE-lol TAR-trate
Generic Name: Metoprolol Tartrate
Brand Name: Lopressor

Do not suddenly stop taking Lopressor. Sharp chest pain, irregular heartbeat, and sometimes heart attack may occur if you suddenly stop Lopressor. The risk may be greater if you have certain types of heart disease. Your doctor should slowly lower your dose over several weeks if you need to stop taking it. This should be done even if you only take Lopressor for high blood pressure. Heart disease is common and you may not know you have it. Limit physical activity while you are lowering your dose. If new or worsened chest pain or other heart problems occur, contact your doctor right away. You may need to start taking Lopressor again.


Tell your doctor or dentist that you take Lopressor before you receive any medical or dental care, emergency care, or surgery.


Tell your doctor if you have a history of diabetes or if you take medicine to lower your blood sugar (eg, glyburide, insulin). Lopressor may hide signs of low blood sugar, such as fast heartbeat. Be sure to watch for other signs of low blood sugar (eg, anxiety, chills, dizziness, drowsiness, fainting, headache, tremor, unusual sweating, vision changes, weakness). Tell your doctor right away if these effects occur.


Lopressor should not usually be used by patients who have a history of certain lung or breathing problems (eg, asthma) or who have a certain type of adrenal gland tumor (pheochromocytoma). It may worsen these conditions. Tell your doctor if you have a history of breathing problems or adrenal gland tumors. If you have these conditions and must take Lopressor, your doctor may need to adjust your dose or prescribe additional medicine to reduce the risk of side effects. Check with your doctor for more information.


Tell your doctor if you have a history of overactive thyroid. Lopressor may hide symptoms of overactive thyroid (eg, fast heartbeat). Do not suddenly stop taking Lopressor; suddenly stopping Lopressor could worsen your condition. Your doctor should slowly lower your dose over several weeks if you need to stop taking it. Check with your doctor for more information.





Lopressor is used for:

Treating high blood pressure, alone or with other medicines; long-term treatment of chest pain; and reducing the risk of death because of heart problems in patients who have had a heart attack. It may also be used for other conditions as determined by your doctor.


Lopressor is a beta-adrenergic blocking agent (beta-blocker). It works by reducing the amount of work the heart has to do (reduces chest pain) and the amount of blood the heart pumps out (lowers high blood pressure). It is also used to stabilize the heart rhythm in conditions in which the heart is beating too fast or in an irregular rhythm.


Do NOT use Lopressor if:


  • you are allergic to any ingredient in Lopressor or to another beta-blocker (eg, propranolol)

  • you have a very slow heart rate (eg, bradycardia), certain types of irregular heartbeat (eg, atrioventricular [AV] block, sick sinus syndrome), moderate to severe heart failure, very low systolic blood pressure (less than 100 mm Hg), or severe blood circulation problems

  • you are taking mibefradil

Contact your doctor or health care provider right away if any of these apply to you.



Before using Lopressor:


Some medical conditions may interact with Lopressor. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have an adrenal gland tumor (pheochromocytoma), an overactive thyroid, or are scheduled to have surgery

  • if you have low blood pressure or a history of heart attack, slow or irregular heartbeat, heart failure, or other heart problems; chest pain or angina; blood circulation problems; or liver problems

  • if you have diabetes mellitus, chronic obstructive pulmonary disease (COPD), bronchitis, breathing problems, or a history of asthma

Some MEDICINES MAY INTERACT with Lopressor. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Amiodarone, bupropion, cimetidine, digoxin, diltiazem, diphenhydramine, disopyramide, flecainide, certain HIV protease inhibitors (eg, ritonavir), hormonal contraceptives (eg, birth control pills), hydralazine, hydroxychloroquine, ketanserin, mefloquine, mibefradil, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), phenothiazines (eg, thioridazine), propafenone, propylthiouracil, quinazolines (eg, alfuzosin), quinidine, reserpine, certain selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine, paroxetine), terbinafine, or verapamil because serious side effects, such as very slow heart rate, very low blood pressure, fainting, severe dizziness, or lightheadedness when standing, may occur

  • Clonidine because stopping it or Lopressor suddenly can lead to a rapid increase in blood pressure

  • Barbiturates (eg, phenobarbital), indomethacin, or phenylpropanolamine because they may decrease Lopressor's effectiveness

  • Bupivacaine, disopyramide, flecainide, hydralazine, ketanserin, or lidocaine because the risk of their side effects may be increased by Lopressor

This may not be a complete list of all interactions that may occur. Ask your health care provider if Lopressor may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Lopressor:


Use Lopressor as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Lopressor is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Lopressor at home, a health care provider will teach you how to use it. Be sure you understand how to use Lopressor. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

  • Do not use Lopressor if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.

  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.

  • If you miss a dose of Lopressor, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Lopressor.



Important safety information:


  • Lopressor may cause drowsiness, dizziness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Lopressor with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Lopressor may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

  • Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.

  • Do not suddenly stop using Lopressor without first consulting your doctor. If your doctor decides you should no longer use Lopressor, you will need to stop Lopressor gradually according to your doctor's instructions.

  • If your doctor has instructed you to check your blood pressure and heart rate regularly, be sure to do so.

  • Do not take any medicines used to treat colds or congestion without first consulting with your doctor or pharmacist.

  • Diabetes patients - Lopressor may hide signs of low blood sugar, such as rapid heartbeat. Be sure to watch for other signs or low blood sugar. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your vision change; give you a headache, chills, or tremors; or make you more hungry. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

  • Tell your doctor or dentist that you take Lopressor before you receive any medical or dental care, emergency care, or surgery.

  • If you have a history of any severe allergic reaction, talk with your doctor. You may be at risk of an even more severe allergic reaction if you come into contact with the substance that caused your allergy. Some medicines used to treat severe allergies may also not work as well while you are using Lopressor.

  • Lab tests, including liver and kidney function, blood pressure, and complete blood cell counts, may be performed while you use Lopressor. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Lopressor should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lopressor while you are pregnant. Lopressor is found in breast milk. If you are or will be breast-feeding while you use Lopressor, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Lopressor:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; diarrhea; dizziness; dry mouth or eyes; gas; headache; heartburn; lightheadedness; mild drowsiness; muscle aches; nausea; pain, redness, or swelling at the injection site; stomach pain; trouble sleeping; unusual tiredness or weakness; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue, unusual hoarseness); blue or unusually cold hands or feet; chest pain; chills, fever, or sore throat; fainting; hallucinations; mood or mental changes (eg, confusion, depression, foggy thinking, short-term memory loss); pounding in the chest; severe dizziness or lightheadedness; shortness of breath; slow or irregular heartbeat; swelling of the arms, hands, and feet; unusual bruising or bleeding; vision changes; wheezing; yellowing of the skin or eyes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Lopressor side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include difficult or slowed breathing; fainting; severe dizziness; very slow heart rate; weakness.


Proper storage of Lopressor:

Store Lopressor at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lopressor out of the reach of children and away from pets.


General information:


  • If you have any questions about Lopressor, please talk with your doctor, pharmacist, or other health care provider.

  • Lopressor is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Lopressor. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Lopressor resources


  • Lopressor Side Effects (in more detail)
  • Lopressor Use in Pregnancy & Breastfeeding
  • Drug Images
  • Lopressor Drug Interactions
  • Lopressor Support Group
  • 8 Reviews for Lopressor - Add your own review/rating


  • Lopressor Concise Consumer Information (Cerner Multum)

  • Lopressor Prescribing Information (FDA)

  • Lopressor Advanced Consumer (Micromedex) - Includes Dosage Information

  • Metoprolol Prescribing Information (FDA)

  • Metoprolol Professional Patient Advice (Wolters Kluwer)

  • Metoprolol Succinate Monograph (AHFS DI)

  • Toprol-XL Prescribing Information (FDA)



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Friday, 6 July 2012

Colace Micro-Enema


Generic Name: docusate (DOK ue sate)

Brand Names: Calcium Stool Softener, Colace, Correctol Softgel Extra Gentle, D-S Caps, Diocto, Doc-Q-Lace, Docu, Docu Soft, Doculase, Docusoft S, DocuSol, DOK, DOS, DSS, Dulcolax Stool Softener, Enemeez Mini, Fleet Sof-Lax, Kao-Tin, Kaopectate Stool Softener, Kasof, Phillips Stool Softener, Silace, Sur-Q-Lax


What is Colace Micro-Enema (docusate)?

Docusate is a stool softener. It makes bowel movements softer and easier to pass.


Docusate is used to treat or prevent constipation, and to reduce pain or rectal damage caused by hard stools or by straining during bowel movements.


Docusate may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about Colace Micro-Enema (docusate)?


You should not use docusate if you are allergic to it, or if you have a blockage in your intestines. Do not use docusate while you are sick with nausea, vomiting, or stomach pain. Do not take mineral oil while using docusate, unless your doctor tells you to.

Ask a doctor or pharmacist before using docusate if you are on a low-salt diet, if you are pregnant or breast-feeding, or if you have recently had a sudden change in your bowel habits lasting for longer than 2 weeks.


What should I discuss with my healthcare provider before using Colace Micro-Enema (docusate)?


You should not use docusate if you are allergic to it, or if you have a blockage in your intestines. Do not use docusate while you are sick with nausea, vomiting, or stomach pain. Do not take mineral oil while using docusate, unless your doctor tells you to.

Ask a doctor or pharmacist if it is safe for you to take docusate:



  • if you are on a low-salt diet; or




  • if you have recently had a sudden change in your bowel habits lasting for longer than 2 weeks.




It is not known whether docusate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether docusate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child younger than 2 years old without the advice of a doctor.

How should I use Colace Micro-Enema (docusate)?


Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.


Take docusate tablets or capsules with a full glass of water. Drink plenty of liquids while you are taking docusate. Do not crush, chew, or break a docusate capsule. Swallow it whole.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. Mix the liquid with 6 to 8 ounces of milk, fruit juice, or infant formula and drink the mixture right away.


Do not take docusate rectal enema by mouth. It is for use only in your rectum. Wash your hands before and after using docusate rectal enema.

Try to empty your bowel and bladder just before using the enema.


Twist off the applicator tip. Lie down on your left side with your knees bent, and gently insert the tip of the enema applicator into the rectum. Squeeze the tube to empty the entire contents into the rectum. Throw away the tube, even if there is still some medicine left in it.


After using docusate, you should have a bowel movement within 12 to 72 hours. Call your doctor if you have not had a bowel movement within 1 to 3 days.


Do not use docusate for longer than 7 days unless your doctor has told you to. Overuse of a stool softener can lead to serious medical problems. Store at room temperature away from moisture and heat.

What happens if I miss a dose?


Since docusate is used as needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting or stomach pain.


What should I avoid while using Colace Micro-Enema (docusate)?


Avoid using laxatives or other stool softeners unless your doctor has told you to.

Avoid using the bathroom just after using docusate enema.


Colace Micro-Enema (docusate) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using docusate and call your doctor at once if you have a serious side effect such as:

  • rectal bleeding or irritation;




  • numbness or a rash around your rectum;




  • severe diarrhea or stomach cramps; or




  • continued constipation.



Less serious side effects may include:



  • mild diarrhea; or




  • mild nausea.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Colace Micro-Enema (docusate)?


There may be other drugs that can interact with docusate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Colace Micro-Enema resources


  • Colace Micro-Enema Side Effects (in more detail)
  • Colace Micro-Enema Use in Pregnancy & Breastfeeding
  • Colace Micro-Enema Drug Interactions
  • Colace Micro-Enema Support Group
  • 0 Reviews for Colace Micro-Enema - Add your own review/rating


  • Docusate Professional Patient Advice (Wolters Kluwer)

  • Colace MedFacts Consumer Leaflet (Wolters Kluwer)

  • Diocto Liquid MedFacts Consumer Leaflet (Wolters Kluwer)

  • Docusate Salts Monograph (AHFS DI)

  • Dostinex Monograph (AHFS DI)

  • Enemeez Mini Enema MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Colace Micro-Enema with other medications


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Where can I get more information?


  • Your pharmacist can provide more information about docusate.

See also: Colace Micro-Enema side effects (in more detail)